Boston Chapter 6: Going Deep Underground

I have never quite understood the romanticization of famous criminals.

I mean, I just don’t get it. People look at, say, the Mafia, or serial killers, and make them out to be some sort of romantic mythic figures, blazing their own path through life, heedless of the laws and mores of ordinary folk and occasionally feeding ordinary folk into wood chippers. I’ve heard that imprisoned serial killers actually get fan mail, often from women who offer them sex or marriage or both, and frankly I find it all bewildering (and just a touch unsettling).

Take Jesse James, for instance. What is it, exactly, that was romantic about this guy? As near as I can tell, the man was an illiterate, slave-owning, narcissistic sociopath who discovered a taste for killing people as a mercenary for the Confederacy and, after the war, privatized his former government service job by robbing banks and murdering clerks, students, tellers, and random passers-by–sometimes while dressed as Ku Klux Klansmen.

Just the sort of person you want babysitting your kid, right?

I mention Jesse James because some hours after leaving the Glore psychiatric museum, and with brains still reeling from the experience, we opted to stop at Meramec Caverns in the once-Confederate state of Missouri.

Meramec Caverns is a large cave system that’s noteworthy for a number of reasons. It’s geologically unique, sporting some of the largest-known limestone formations in the world. It was a part of the folklore of the Osage tribe of Native Americans, who used it for shelter. The cave system was said to be used as a waystation on the Underground Railroad prior to the Civil War.

And apparently, Jesse James hid in it once.

Of all these factoids, it’s the last one that gets the most press. In fact, as soon as you arrive, there’s no question at all about what you’ll be getting for your entertainment dollar:

I quite like cave systems, so when the idea of stopping in Stanton to check out the caves was floated, I offered an enthusiastic “yes” vote. We arrived just before closing, and bought our tickets from a fairly indifferent park ranger who explained to us that the caves were once used as a hiding place by Jesse James. From there, we proceeded through a huge cavern that’s been turned into a gift store to the tour entrance, where another park ranger told us he’d be taking us on a guided tour and that the cave system was once used as a hiding place by Jesse James. In case we were wondering why the cave was famous, a neon sign helpfully advertised the little-known fact that the cave was once used as a hiding place by Jesse James.

We walked past a model of a small wood cabin that was, apparently, similar to a cabin once stayed in by Jesse James, through an enormous chamber that was in times past used as a ballroom, and then brought past a couple of statues which, the tour guide explained, were placed on the spot where a sheriff had discovered boxes known to have been stolen by Jesse James.

Occasionally, I consider the fact that more people know about small-time thugs like Jesse James than about Norman Borlaug, the dude who got considerably less fame by saving the lives of over a billion people, but I digress.

The cave is actually quite lovely. In a lot of ways, it’s absolutely the perfect, Platonic ideal of a cave, with huge chambers and small passages and even an underground river. An underground river! How cool is that? Our guide explained that when Jesse James holed up there, the local sheriff cordoned off the entrance, but Jesse James was able to make his escape by swimming down the river and discovering a heretofore-unknown exit.

It’s quite dramatic all on its own.

Apparently feeling that the natural wonder of sparkling, crystal-clear water rushing underground along a path that’s dripping with all manner of limestone formations isn’t enough, the cave’s owners have put in a bunch of colored lights, to make it even more dramatic.

I do have to admit it’s pretty.

The cave is altogether lovely even when it’s not being lit like a bad 80s hair metal band.

The passing time was freaking our travelling companion Erica out a bit, as she doesn’t like driving at night, but Claire and I had quite a lot of fun on the tour. At least those bits of it that weren’t about Jesse James, who as I may have mentioned was a murderous, sociopathic thug with bad hair and in whom I am almost entirely uninterested. I got a lovely picture of Claire some way through the tour.

Shortly after this photo was taken, we arrived at the end of the tour.

I have no pictures of what awaited us there. If I did have any pictures, I would be reluctant to share them with you, Gentle Reader, on the grounds that, unlike Jesse James, I am not a violent, sociopathic thug with bad hair, and I bear you, my blog-reading public, neither malice nor ill will.

Indeed, it is with some trepidation that I even describe the horrors that await those who take the tour in mere words, for the experience is not for the faint of sanity.

Imagine, if you will, a vast, bowl-shaped chamber upon whose sides have been poured many tons of concrete, to better accommodate the stadium seating set therein. Imagine that this seating faces a quite lovely, and very large, waterfall of solid rock, the slow accumulation of limestone carried by the endless drip of water over a period of hundreds of millions of years–a breathtaking example of nature’s subtle and profound beauty.

And now imagine the part ranger–the one who talked to us about Jesse James–playing a tape recording of what might once have been stirring patriotic music, many many decades ago, while presenting a light show against that magnificent backdrop of rock, complete with projected images of the American flag, by…

…I swear I am not making this up…

furiously toggling a large panel full of light switches to make colored lights flash on and off.

It’s a spectacle that I don’t think could be found anywhere else on Earth besides a cave in the American South, a simultaneously cheap and cheesy display of faux patriotism that’s almost, but not quite, a parody of itself, and so very, very, desperate in its sincerity. I don’t think I’ve ever seen anything quite like it, and the memory of the spectacle has, I feel, filled a much-needed gap in my life.

I’m not quite sure how we left the cave. It’s entirely possible that the combination of lights and sounds to which we were exposed had temporarily stunned my ability to form short-term memory, my brain seeking some Freudian mechanism to cope with the essentially un-copeable. Or, and perhaps more sinister, it’s possible that we were exposed to some highly advanced form of neurobiological programming, planting the seeds of behavioral conditioning deeply into our psyches, awaiting only a television ad for Fruity Oaty Bars to transform us into unstoppable killing machines, unwitting foot soldiers for the new Confederacy or something.

Our behavioral conditioning for our new Jesse-James-loving, cave-dwelling Southern overlords complete, we headed out into the night. The next day would bring with it an experience that the eight-year-old in me will never forget.

What is transhumanism?

A couple of weeks ago, I realized that I spend a fair bit of time both here in my blog and over on my Web site writing about transhumanism, but I’ve never actually written an article explaining what it is.

Wikipedia defines transhumanism as “an international intellectual and cultural movement that affirms the possibility and desirability of fundamentally transforming the human condition by developing and making widely available technologies to eliminate aging and to greatly enhance human intellectual, physical, and psychological capacities.” That’s true in a sort of reductionist sense, but I’m not sure it’s a terribly useful definition.

If I were to define transhumanism, I’d say that it’s an idea whose premise is that human nature is not some fixed quantity, forever unalterable; it’s something that is a consequence of our biology and our environment, and it can be changed. Furthermore, advances in technology and in our understanding of biology, chemistry, and physics, give us the power to change it as we wish–to take evolution from a blind, undirected process to a process that we can make choices about. It’s predicated on the idea that we can, if we so desire, choose what it means to be human.

A great deal of conventional thought has always held on to the idea that “human nature” is something that’s a fundamental part of who we are, forever unalterable. Certain aspects of the human condition, from mortality to aggression, from disease to territoriality, have always been thought of as fixtures of the human condition; no matter how our society changes, no matter what we learn, these things have been assumed to be an immutable part of us.

Transhumanist thought holds that this isn’t so. We are physical entities, whose nature comes from an extraordinarily complex dance of biochemical processes happening in our bodies. The way we respond to stress, the way we behave, the way our bodies suffer gradually increasing debility, all these things are the consequence of the physical processes happening inside our bodies and brains.

And they can change. Improved diet has made us qualitatively different from our neolithic ancestors–taller, longer-lived. Thousands of generations living in large numbers have made us more able to function in complex social environments; we have, in a sense, domesticated ourselves.

Right now, advances in biotechnology offer to revolutionize our view of who we are. What if aging and death were no longer inevitable? What if we could invent ways to repair genetic disorders? What if the human brain, which is a physical organ, could be modeled inside a computer? What if we could develop techniques to make our brains operate more efficiently? These sound like science fiction to a lot of people, but every single one of them is the subject of active research in labs around the world right now.

Transhumanism is a highly rationalist idea. It rejects the notion that human beings are corrupt, doomed to suffer and die as a result of a fall from grace. Rather, it postulates that the things that make us who we are are knowable and comprehensible; that the state of being human is a fit subject for scientific inquiry; and that as we learn more about ourselves, our ability to shape who we are increases.

The implications of these ideas are deeply profound. Transhumanist philosophy is built from the notion that things like indefinite lifespan, brain modeling, and improvement of human physical and intellectual capacity are both possible and desirable. Transhumanism, therefore, is profoundly optimistic.

It is not, however, Utopian. Like all new technologies, these things all have potential consequences whose outlines we can’t see clearly yet. Therefore, transhumanism tends to be concerned not only with the possibility of biomedical technology but also its ethics; the study of transhumanism is, in large part, the study of bioethics. Who controls the direction of new, disruptive biomedical technology? What does it mean to be a “person;” is an artificial intelligence a person? How should new biomedical technology be introduced into society? How can it be made available democratically, to everyone who wishes it? What role is available to people who for whatever reason don’t choose to benefit from new advances in medical understanding?

At its core, transhumanism is deeply pragmatic. Since it seems likely that biotechnology is going to improve over time whether we think about the implications of it or not, transhumanists think about things like bioethics, immortality, and the nature of consciousness in concrete, real-world terms, rather than as philosophical exercises. One of the things I most like about transhumanism is its drive to ask questions like “How can we maximize the benefit of what we are learning while maintaining human agency, dignity, and the right to choose?” Transhumanists are invited to be skeptical about everything, including the premises of transhumanism. It is quite likely that whatever views of the future we dream up will be flawed, as most prognostication tends to be. But by getting into the habit of examining these ideas now, and of considering the moral and ethical dimensions of our accelerating understanding of biology, we can at least train ourselves to get into the habit of asking the right questions as new breakthroughs come.

I Know Why the Caged Bunny Sings

Last November, zaiah and I hosted an 11/11/11 party, because 11/11/11 is an aesthetically pleasing date and parties are fun.

My sweetie emanix flew into town from London to attend. zaiah‘s Canadian boyfriend had planned to be there as well, though last-minute illness delayed his trip, with the result that only three nations were represented instead of four. The party was great fun; zaiah‘s cage was broken in for the first time, there were enough Jell-O shots to sink a battleship (at least a reasonably small battleship, whose crew were perhaps not the heaviest of drinkers), a large pile of Barbie dolls was cast into bondage for the benefit of some tentacle monsters, and I erroneously recorded elsewhere that at one point a total of three threesomes were going on simultaneously in the basement. The correct number of threesomes is four.

However, none of that is what I came here to talk about. I actually came here to talk about what happened afterward.

A couple of days later, emanix happened to mention in passing that she’d quite like to be stuck with needles, and that on a possibly related note she brought an assortment of birthday candles with her.

As I may have mentioned earlier, there just so happened to be a quite large cage, trimmed in LED rope lights, sitting in the living room from the party. It turns out that normal, regulation-sized birthday candles are just a tiny bit too wide to fit into the hub of normal, regulation-sized needles–a sad commentary on the lack of coordination among standards-setting bodies, and something that will be remedied when I rule the world, oh yes. A bit of work with a kitchen knife soon remedied that difficulty, however, and we were ready to begin.

Shortly thereafter, there was, as sometimes happens, a bunny in a cage.

For reasons not clear to your humble scribe, I often seem to get this look when I spend time with emanix.

The photos that lie beneath this cut are, unless your work environment is a statistical outlier, SO not safe for work that even thinking them while in the workplace may be cause for termination. Click here only if you’re OK with nudity, needles, fire play, and caged bunnies.

Boston Chapter 5: Little Hospital of Horrors

I’m a little surprised, whenever I think about it, that human beings were able to successfully treat, much less cure, any disease whatsoever prior to…oh, I don’t know, about 1977 or so.

Seriously, whenever one picks up a history book or (God forbid) a book on medical technology, it seems that before the advent of Star Wars all we had were superstition, stone knives, and dried tiger penises. In fact, even to this day, many people’s sum total understanding of basic biology scarcely extends beyond stone knives and dried tiger penises–but I didn’t come here to talk about the alt-medicine crowd.

Instead, I came here to talk about Boston. Err, not Boston itself, you understand, but our journey toward that fabled (and by now near-mythical) Xanadu, where my friend Claire had been accepted to a university or a Thunderdome or something. By this point, it was all getting a bit blurry, what with the heat and the prairie dogs and the Jesus of Wheat and all.

When we next set out, with Erica driving and me trying with only modest success to deal with a client’s crisis of some sort about something or other, the temperature was already nudging toward the triple digits. Frankly, I’m sometimes a bit surprised that any human being successfully survived summer in the Midwest prior to the invention of air conditioning. We had determined days before to make a stop at the Glore Psychiatric Museum in St. Joseph, Missouri. We had a book which called it one of the 50 “most unusual museums in the United States.” I’m not quite sure who made that list or on what criteria it was based, but the Museum of Spam (the quasi-meat product, not the email full of Nigerian princes and penis pills) is on the list, and that’s good enough for me.

The Glore Psychiatric Museum is housed in what’s left of Missouri State Lunatic Asylum No. 2–yep, that was its official name. Now, I’ve seen a number of Hollywood films involving a small number of friends who happen to be traveling alone across the country. All of them recommend stopping for a time in the ruins of an old lunatic asylum, so stop we did.

The first thing one sees upon entering the museum is this old newspaper illustration, apparently dating back to the time of the asylum’s founding, which depicts life in an insane asylum as a rather proper Victorian affair replete with formal tea and, I don’t know, Badminton games or something. “I say, old chap, after our noonday repast, would you fancy a stroll through the park, followed by a rousing cricket match?” “That sounds delightful, dear fellow, but I rather think we should postpone the afternoon meal until after our sport.” “After our sport? I say, are you mad?” “Quite so, old sport!”

We ventured farther in, where we were met by a cheerful gentleman who assured us that no psychotic, supernatural offspring of crazed serial killers bent on bloody vengeance had been seen ’round the grounds in almost a fortnight, so we were confident that our stay would be pleasant and free of the bother one normally can expect from such things.

It doesn’t take very long to realize that anyone unwise enough to be crazy prior to the age of Pac-Man was in for rather sorry treatment at the hands of his fellow man. The museum has a floor full of devices which had previously been used to “treat” mental illness, and to my (admittedly untrained) eye, rather a lot of them looked indistinguishable from the sorts of devices the Inquisitors might use. Take these gadgets, for example:

The chair on the left was used to calm patients by restricting their mobility. Sometimes, apparently, for weeks. The gizmo on the left was designed to confine a person in a very small box which would then be spun ’round at high speed until the unfortunate occupant passed out or threw up, or both–presumably on the premise that a vomiting mental patient is better than a mental patient who…um, isn’t vomiting, or, err, something. The precise details of the therapeutic modality are beyond my grasp of the art.

And the definitions of “mentally ill” were as all over the map as the treatments. In ages past, an unmarried woman who wanted children might be confined to an asylum, as might a married woman who didn’t. (True fact: the dude who invented the diagnoses of “nymphomania” included diagnostic criteria such as a fondness for chocolate and a penchant for reading works of fiction, I swear I am not making this up.)

It rather seems, all in all, that the considered opinion of the entire medical establishment over a very long span of time was that the mentally ill were just being stubborn, and merely needed a few nasty knocks about the head to get them to cut it out. This seems to your humble scribe rather like saying a legless man is simply being lazy, and all he needs is a good swift kick in the pants to get him on his feet again…though I didn’t come here to talk about the Republican party, either.

The general theme of “knock them about a bit ’til they learn to cut it out” as a treatment modality for cognitive and emotional impairment continues through quite a lot of the medical equipment on display:

Some of the items in their collection would look, I have to say, right at home here in my dungeon, and I wouldn’t mind building something like that long cage on the left…but only for people who are of sound and willing mind. I may be a mad scientist, but I’m not, well, crazy, you know? At least not like the folks who actually thought these things would do some good.

A number of other displays commemorated the sometimes colorful and occasionally fatal eccentricities of a few of the hospital’s more outstanding patients. Take this one, for example, which is just kind of weird until you know what it is, at which point it becomes weird and gross.

This bizarre work of art was made by hospital staff, not by a patient, out of the materials found in a patient’s…err, stomach. The patient in question, you see, had what would today be called obsessive-compulsive disorder, but the particular manifestation of her obsession lay in eating any little bits of sharp pointy metal things that she could get her hands on. Which, as you might expect, eventually killed her.

See? Weird and gross. I did try to warn you.

This guy, on the other hand, was straight out of the X-Files:

The story, as near as I can remember it, is that there was this dude who was completely convinced he was sane, while all the people around him thought that he was stark raving mad. He was utterly convinced that there were railroad box cars containing evidence of his sanity being kept at an undisclosed location, and he wrote about them obsessively. Somewhere along the way, he also became convinced that the television set in his room contained a secret mechanism by which he could send messages to the vague and sinister forces hiding the box cars from him, or perhaps to agents opposing those sinister forces (it’s not entirely clear to your humble scribe) so he wrote long, rambling, incoherent letters about box car numbers and train routes and railway schedules and stuff, or something, and tucked them inside the television set, until it eventually quit working.

Which, I reckon, wasn’t actually the outcome he had hoped for. It’s bad enough when a secret conspiracy has plotted to conceal evidence vital to your sanity in railway cars; it’s even worse when you can’t watch next week’s Gunsmoke on television.

This next bit is a tiny section of a huuuuuge piece of embroidery, created by hand by a patient on what I believe to be a hospital bedsheet.

We puzzled over it for quite a while. Reading it is rather like trying to track a coherent thought through a untrodden jungle the way a traditional Chinese doctor might track a tiger across the savannah, following its telltale traces in the slightest disturbance of underbrush, before shooting it in the head and drying out its penis to make phony aphrodisiacs that are sold in small glass vials from musty shops whose owners don’t really give a toss about the extinction of a noble species for the sake of superstition…but I digress.

This display one was one of my favorites.

One should not court another man’s wife if one wishes to avoid a sticky fate. You heard it here first.

The basement of the old hospital, where we ended up after we decided to separate and explore the ancient lunatic asylum separately just as Hollywood has taught us to do, bore a large steel door with these markings:

It is unclear to your humble scribe exactly what sort of disaster supplies one keeps in the morgue, or indeed what eventuality those supplies are intended to ward against. I can only imagine it’s not a zombie-related disaster, as keeping one’s zombie-related disaster supplies in the same location as the corpses of the newly dead is likely to result in a certain inconvenience.

We fled the museum through the gift shop, where many commemorative items were available for sale (“Relive the experience again and again!”), and then were once again on our way to Shangri-La. There were by now only a couple of adventures left before our encounter with the Guatemalans and our renewed appreciation to the full fury of Nature’s watery wrath, but those tales will need to wait for another telling.

Christmas Puppy!

zaiah‘s dog had seven puppies on Wednesday, and they’ve been growing like cute fuzzly little weeds ever since. Here’s one of the little girls, snuggling with zaiah this afternoon, presented for your viewing pleasure. Me, I’ll be over here DYING OF CUTE.

Review: Kinklabs Neon Wand

Back when I was married and living in Tampa, one of my favorite sex toys in the sex toy drawer box closet was a violet wand. It’s a gadget that you plug glass electrodes into and then plug into the wall. When you turn it on, it makes a buzzing noise and the glass electrodes turn purple, and then when you touch someone with the electrodes you get a sensation that’s like…

Well, it’s kinda hard to describe what it’s like. A lot of folks (like me!) who don’t like electrical play still like violet wands, because they don’t really feel like electric shocks. It’s more like little teensy hot needles caressing your skin. There are lots of different shapes of electrodes, that all make different sensations, but that’s the basic theme.

They’re amazing toys. They’re also very spendy. The violet wand I used to have cost me about $700, so when I lost it, I couldn’t afford to replace it, and I’ve been missing it ever since.

Recently, JT’s Stockroom sent me a neon wand as part of a promotion. And, to be honest, I’ve been waiting for someone to realize the market for cheap, reliable violet wands for rather a long time.


This is the Kinklab Neon Wand. If you really want to get technical, it’s not a violet wand, though the reasons that’s true are largely academic.

But, since this journal has never been afraid to venture forth into the academic, I’ll explain why; click here if if you’re interested.

It’s Beginning to Look a Lot Like Tentacles!

For the past several years, zaiah has wanted to make a Christmas tree with a “tentacle rape demons and the schoolgirls they love” theme.

This year, we finally made it happen.

We managed to obtain (please don’t ask me how) quite a large pile of Barbie dolls. In November, we hosted an 11/11/11 party which featured, among other things1, a lot of folks eating Jell-O shots and putting the Barbies into shibari rope harnesses. The Barbies serve as the innocent victims, which as we all know every tentacle monster needs plenty of in order to grow up big and strong.

Click here for more pictures…

Another podcast interview!

A couple weeks back, I had the opportunity to meet Shira B. Katz of the Pedestrian Polyamory podcast. What followed was a conversation about polyamory, transhumanism, mad science, programmable sex toys, and all sorts of other stuff, which you can listen to here.

The interview was great fun. I’d definitely love to do it again.

Microsoft’s Future: Just Like the Present, Only More

Recently, Microsoft’s PR department cobbled together a whizbang vision of our technological future, as seen through the lens of Microsoft’s ideas about technology and man/machine interface.

It’s a remarkable bit of work, though likely not quiiiiiite for the reasons Microsoft might think. If you haven’t seen it yet, here it is–it (kind of) requires sound and is safe for work, unless perhaps you work for Google or Apple.

Now, a few things struck me when I watched this video.

Not just the sterility of it, or the fact that in Microsoft’s future we’re all upper middle class, or the fact that nobody actually talks to anyone else. Those things are all true, I suppose, and reflect Microsoft’s corporate identity as a painfully introverted, socially awkward, borderline-autistic Lex Luthor, as befits its founder and cultural leader Bill Gates.

No what struck me as I watched this video was the fact that there are no disruptive technologies. Everything here is just an evolution of tech we already have.

Displays mounted on walls, instead of displays being walls. Handheld cell phones with 3D screens, instead of completely virtualized input and output (say, contact lenses with 3D displays). “Computing devices” being distinct entities from other devices. Cars that have displays embedded in their windows, rather than cars whose windows–or paint jobs!–are displays. And everywhere swipe, swipe, push, and swipe.

It reads to me as if Microsoft in 1982 had released a version of the future where keyboards are really thin and we all type commands into command prompts in glorious 24-bit color instead of using GUIs…you know, rather like Linux users do today.

When I look at this video, what I see is the Jetsons. Remember the Jetsons, the cartoon that told us that the future would have us living in glass-domed pods floating in the air, but that gender roles and social norms would still be just like they were in 1959? In the Jetsons future, instead of making robotic vacuum cleaners, you make robotic maids that push regular vacuum cleaners around.

Now, I get it. Disruptive technologies are, by their nature, hard to predict. Visions of the future always end up getting it wrong, sometimes in ways that look silly.

But man, Microsoft isn’t even trying. To them, the future is just like the present, only longer. What’s missing from their vision isn’t just imagination; it’s humanness. It’s a sense of how people use technology, and how the street finds its own uses for things.

To me, that, more than anything else, is Microsoft’s failure.

Science Literacy: Of Pickles and Probability

STUDY PROVES THAT PLACING A PICKLE ON YOUR NOSE GRANTS PSYCHIC POWERS

For immediate release: Scientists at the Min Planck Institute announced today that placing a pickle on your nose can improve telekinetic ability.

According to the researchers, they performed a study in which a volunteer was asked to place a pickle on her nose and then flip a coin to see whether or not the pickle would help her flip heads. The volunteer flipped the coin, which came up heads.

“This is a crowning achievement for our research,” the study’s authors said. “Our results show that having a pickle on your nose allows you to determine the outcome of a coin-toss.”

Let’s say you’re browsing the Internet one day, and you come across this report. Now, you’d probably think that there was something hinkey about this experiment, right? We know intuitively that the odds of a coin toss coming up heads are about 50/50, so if someone puts a pickle on her nose and flips a coin, that doesn’t actually prove a damn thing. But we might not know exactly how that applies to studies that don’t involve flipping coins.


So let’s talk about our friend p. This is p.

p represents the probability that a scientific study’s results are total bunk. Formally, it’s the probability that results like the ones observed could occur even if the null hypothesis is true. In English, that basically means that it represents how likely it is to get these results even if whatever the study is trying to show doesn’t actually exist at all, and so the study’s results don’t mean a damn thing.

Every experiment (or at least every experiment seeking to show a relationship between things) has a p value. In the nose-pickle experiment, the p value is 0.5, which means there is a 50% chance that the subject would flip heads even if there’s no connection between the pickle on her nose and the results of the experiment.

There’s a p value associated with any experiment. For example if someone wanted to show that watching Richard Simmons on television caused birth defects, he might take two groups of pregnant ring-tailed lemurs and put them in front of two different TV sets, one of them showing Richard Simmons reruns and one of them showing reruns of Law & Order, to see if any of the lemurs had pups that were missing legs or had eyes in unlikely places or something.

But here’s the thing. There’s always a chance that a lemur pup will be born with a birth defect. It happens randomly.

So if one of the lemurs watching Richard Simmons had a pup with two tails, and the other group of lemurs had normal pups, that wouldn’t necessarily mean that watching Mr. Simmons caused birth defects. The p value of this experiment is related to the probability that one out of however many lemurs you have will randomly have a pup with a birth defect. As the number of lemurs gets bigger, the probability of one of them having a weird pup gets bigger. The experiment needs to account for that, and the researchers who interpret the results need to factor that into the analysis.


If you want to be able to evaluate whether or not some study that supposedly shows something or other is rubbish, you need to think about p. Most of the time, p is expressed as a “less than or equal to” thing, as in “This study’s p value is <= 0.005″. That means “We don’t know exactly what the p value is, but we know it can’t be greater than one half of one percent.”

A p value of 0.005 is pretty good; it means there’s a 0.5% chance that the study is rubbish. Obviously, the larger the p value, the more skeptical you should be of a study. A p value of 0.5, like with our pickle experiment, shows that the experiment is pretty much worthless.

There are a lot of ways to make an experiment’s p value smaller. With the pickle experiment, we could simply do more than one trial. As the number of coin tosses goes up, the odds of a particular result go down. If our subject flips a coin twice, the odds of getting a heads twice in a row are 1 in 4, which gives us a p value of 0.25–still high enough that any reasonable person would call rubbish on a positive trial. More coin tosses still give successively smaller p values; the p value of our simple experiment is given (roughly) by 1/2n, where n is the number of times we flip the coin.


There’s more than just the p value to consider when evaluating a scientific study, of course. The study still needs to be properly constructed and controlled. Proper control groups are important for eliminating confirmation bias, which is a very powerful tendency for human beings to see what they expect to see and to remember evidence that supports their preconceptions while forgetting evidence which does not. And, naturally, the methodology has to be carefully implemented too. A lot goes into making a good experiment.

And even if the experiment is good, there’s more to deciding whether or not its conclusions are valid than looking at its p value. Most experiments are considered pretty good if they have a p value of .005, which means there’s a 1 in 200 chance that the results could be attributed to pure random chance.

That sounds like it’s a fairly good certainty, but consider this: That’s about the same as the odds of flipping heads on a coin 8 times in a row.

Now, if you were to flip a coin eight times, you’d probably be surprised if it landed on heads every single time.

But, if you were to flip a coin eight thousand times, it would be surprising if you didn’t get eight heads in a row somewhere in there.


One of the hallmarks of science is replicability. If something is true, it should be true no matter how many people run the experiment. Whenever an experiment is done, it’s never taken as gospel until other people also do it. (Well, to be fair, it’s never taken as gospel period; any scientific observation is only as good as the next data.)

So that means that experiments get repeated a lot. And when you do something a lot, sometimes, statistical anomalies come in. If you flip a coin enough times, you’re going to get eight heads in a row, sooner or later. If you do an experiment enough times, you’re going to get weird results, sooner or later.

So a low p value doesn’t necessarily mean that the results of an experiment are valid. In order to figure out if they’re valid or not, you need to replicate the experiment, and you need to look at ALL the results of ALL the trials. And if you see something weird, you need to be able to answer the question “Is this weird because something weird is actually going on, or is this weird because if you toss a coin enough times you’ll sometimes see weird runs?”

That’s where something called Bayesian analysis comes in handy.

I’m not going to get too much into it, because Bayesian analysis could easily make a post (or a book) of its own. In this context, the purpose of Bayesian analysis is to ask the question “Given the probability of something, and given how many times I’ve seen it, could what I’m seeing can be put down to random chance without actually meaning squat?”

For example, if you flip a coin 50 times and you get a mix of 30 heads and 20 tails, Bayesian analysis can answer the question “Is this just a random statistical fluke, or is this coin weighted?”

When you evaluate a scientific study or a clinical trial, you can’t just take a single experiment in isolation, look at its p value, and decide that the results must be true. You also have to look at other similar experiments, examine their results, and see whether or not what you’re looking at is just a random artifact.


I ran into a real-world example of how this can fuck you up a bit ago, where someone on a forum I belong to posted a link to an experiment that purports to show that feeding genetically modified corn to mice will cause health problems in their offspring. The results were (and still are) all over the Internet; fear of genetically modified food is quite rampant among some folks, especially on the political left.

The experiment had a p value of <= .005, meaning that if the null hypothesis is true (that is, there is no link between genetically modified corn and the health of mice), we could expect to see this result about one time in 200.

So it sounds like the result is pretty trustworthy…until you consider that literally thousands of similar experiments have been done, and they have shown no connection between genetically modified corn and ill health in test mice.

If an experiment’s p value is .005, and you do the experiment a thousand times, it’s not unexpected that you’d get 5 or 6 “positive” results even if the null hypothesis is true. This is part of the reason that replicability is important to science–no matter how low your p value may be, the results of a single experiment can never be conclusive.