The Pathologizing of Sexual Disinterest

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In 2019, the FDA approved the drug bremelanotide for use in female hypoactive sexual desire disorder.

Bremelanotide was discovered a bit by accident. The tiny pharmaceutical company that developed it, Palatin Technologies, was looking for a drug that would let you tan without exposure to light (tanning is the result of certain biochemical changes that are usually triggered by exposure to ultraviolet light, but they thought, what if that change could be tipped off by a drug?)

It didn’t work well, but it did, to the researchers’s surprise, do something else: it made some people in clinical trials super-duper extra special horny. In search of a sunless tanning agent, they discovered the world’s first true aphrodisiac.

Fast forward, skipping over a nasal spray trial that was halted in 2004 ostensibly over fears of blood pressure spikes but, behind the scenes, possibly also because the Bush administration’s FDA didn’t like the idea of a real aphrodisiac (women’s sexuality has always, always been political), some licensing agreements, changes of hands, and so forth, in 2014 bremelanotide was approved as an injectable under the trade name Vyleesi. It has not exactly set the world on fire, likely in part because injectible drugs are not generally popular.

It’s also approved only in women, not men, because once again, women’s sexual desire has always been political. (Men can be dagnosed with male hypoactive sexual desire disorder, but the standard treatment modalities are talk therapy and testosterone supplements, because of course the normal state of men is to be horny all the time, so if you’re not horny you either have psychological problems or you don’t have enough testosterone…but I digress.)

I’ve tried it. It’s available from custom peptide synthesis houses, and man, in me (and about half the people who try it) it hits like a truck. There’s nothing subtle about it, no “hmm, is it working, I can’t tell?”, it’s like being flattened by a train. About half an hour after I take it, I’m ready to kick a hole in a vrick wall, and I don’t mean with my foot.

Now, I honestly think this is a good thing. This is in fact a point that Eunice and I make in the Passionate Pantheon novels, our book series set in a post-scarcity society. People in the City have access to “blessings,” sort of like drugs that allow their users to tailor their subjective experiences in almost any way they can imagine.

The reason being, everything that extends human agency, anything that enables people to be who they want to be and make the choices they want to make, is a force for good. Human agency is a desireable goal.

And honestly, I do have that feeling about aphrodisiacs. I personally know people who aren’t generally horny who would like to be. Something that gives you control over your own libido, allowing you to tailor it to what you want it to be? That’s a boon.

And yet…

I find it highly strange that Vyleesi is only available by prescription to women. The cultural narrative is that women should feel retiscent about sex, so a litle pharmacological boost to their libidos is reasonable and normal, but if men don’t want sex we need to find out what’s really wrong with them.

I bet the fact that Vyleesi is available to women but not men sends a message that a lot of women hear loud and clear: if you’re not horny enough for your man, you need medication. In a world where people all had about the same range of autonomy, bremelanotide would be unremarkable; in the world as it is, I worry that there will be those who want it not out of desire to be more horny, but out of fear that they need to please their partners.

Mind you, I am still cautiously optimistic that available of a real aphrodisiac is a good thing, generally speaking. But i see potential for the pathologization of people (by which, of ourse, I mean mostly women) who aren’t interested in sex, or who are fine with having a low libido, and making it available only to women kind of shows where society puts the blame for sexless relationships.