Interesting news on obesity and Alzheimer’s (damn, I’m posting a lot today!)

First, from wldrose, Vaccine may target obesity in the future

When babies receive shots against diseases like polio and measles, their vaccinations may in the future include protection against getting fat, according to researchers.

Infection by certain pathogens triggers rapid increases in fatty tissue in animals, Nikhil Dhurnadha told the annual meeting of NAASO, the Obesity Society, in this western Canadian city.

At the same time, the discovery that many more obese people than normal-weight people have been exposed to a certain virus suggests a link between obesity and viral infection…

Dhurandhar became interested in viral causes of obesity while working as a family physician in Bombay in the 1980s, during a severe outbreak of SMAM1, an adeno virus that kills chickens.

A friend noticed that the dead chickens were unusually fat, with enlarged livers, kidneys, low cholesterol levels and an atrophied thymus gland…

“In 10 years, people may be able to walk into a clinic and be told that their obesity is due to X cause, such as genes, the endocrine system, or pathogens. That may have a more productive outcome than a blanket treatment right now, (which) is not very successful,” said Dhurandhar.

And because viruses are hard or impossible to treat, he said, prevention through vaccines will be key.”


And this one, from shamangirl: Good News for Pot Smokers

An oft-mentioned danger of marijuana smoking—so widely believed that the smokers themselves admit it all the time—is that it kills your brain cells.

But a new study has found that one of marijuana’s active ingredients actually helps produce new brain cells, and this is correlated with anxiety-reducing effects…

[T]he new study found that rats given heavy doses an artificial version of a potent, active ingredient of marijuana grew new brain cells.

In the journal’s November issue, Xia Zhang and colleagues from University of Saskatchewan found that creation of new brain cells was aided by a “potent and synthetic cannabinoid,” or man-made version of a compound extracted from marijuana.

The rats also exhibited less anxiety- and depression- like behavior after a month of the treatment, the study found.

It’s hard to find good protesters these days.

Every day, on my way to work, I drive past a small women’s clinic. Last Tuesday, there was a group of about five or six people standing on the sidewalk in front of the clinic, waving signs showing pictures of fetuses. They’d unfurled a huge yellow banner that they’d placed across the sidewalk, reading “ABORTIONIST!” in large block letters with an arrow pointing at the clinic.

On Friday, the number of protestors had dwindled to three. The big yellow banner was gone–possibly because it had been blocking the sidewalk, or possibly because it was just too much hassle to set up. (Putting up a six-foot-long banner is more work than it seems.)

Saturday and Sunday, nothing. Apparently, protecting the unborn children is important, but not something you’d want to, y’know, give up a weekend for.

Monday and Tuesday, the same three protesters were back. Fewer signs this time, and they just seemed all so…disspirited. Today, the protest had collapsed to a single dishevled man, who looked for all the world like he was homeless, standing in front of the clinic and shaking his fist and screaming incoherently, and, bizarrely, pulling branches off the large tree that sits in the corner of the lot overhanging the sidewalk. I filled my car with gas at the gas station next to the clinic and watched him for a while.


Now, it used to be, back in the day, that people took this protesting thing a lot more seriously. I moved to Tampa in 1992, and then as now, my path to work took me past the clinic every day. (Funny thing, life.)

Back then, there were always about twenty or thirty protesters outside the clinic, every day, rain or shine. I worked at a place called Printgraphics at the time, and one of the protest organizers actually came into the ship once, asking me to design some anti-abortion signs and placards for him. I declined, and he went away and got someone else to do it for him.

But I digress.

They were there every day, chanting and waving signs and holding prayer vigils to, I don’t know, call down a rain of toads on the place or something. The toads never materialized, but that didn’t seem to bother them.


And then, overnight, it all just kinda fell apart. I can even point my finger to the moment when it happened.

It started one day when a young couple and a doctor walked up to the clinic. Someone in the group of protesters thought that saving an unborn child’s life was just absolutely the most important thing imaginable, and such an end justified any means, and he started throwing rocks at them. Next thing you know, a bunch of people had joined in, and showered the couple and their doctor with rocks and bottles. Made the papers and everything.

Problem was, they weren’t going in for an abortion. As it turns out, the couple were going to the clinic because they were trying to conceive. The doctor? He wasn’t an abortion doctor; he was a fertility doctor.

The point was well and truly driven home a few nights later, when one of the protesters decided to vandalize the clinic. The clinic was surrounded with a chain link fence at the time (it’s since been replaced with a more attractive metal fence), and he decided to ram his car through the fence, and…

At this point, I need to stop and digress for a moment. You know those Hollywood movies where you see someone, usually some hero with a beautiful and sexy young woman in his protection, drive a car through a chain-link fence? Forget it. It doesn’t happen that way.

You see, chain link is flexible and giving, but it’s also very, very strong. There ain’t no way you’re driving through a chain-link fence in anything short of an armored, treaded vehicle like a tank or a self-propelled howitzer. It’s not gonna happen.

What DOES happen, in the real world, is that the fence bows, and the car rides up onto the fence and gets caught.

Which is exactly what happened to the hapless protester. His car got hopelessly hung up on the fence and he couldn’t figure out how to free it, so he eventually just abandoned it and walked away.

I saw it there, still hung up on the fence, the next day when i drove to work. the police came, ran the registration, picked the guy up, and that was that.

After that, the protests ended. They just plain stopped, and stayed stopped for years. Too embarrassing, I suppose.


In a way, that’s been a microcosm for the organized anti-abortion movement in the nation as a whole–arguably the most inept and ineffective social movement the nation has ever seen. Groups like Randall Terry’s Operation Self-Aggrandizement Operation Rescue have been good at getting newspaper inches, and have proven very adept at raising money from the faithful. Some of that money goes to administrative costs, a lot of it goes to keeping Randall Terry in his signature $1,000-a-pair alligator-skin boots, and the rest of it seems to be spent on researching new and ever more spectacular ways for the movement to shoot itself in the foot.

Now, the Senate still tosses the issue around whenever they feel like dodging real work, like getting runaway government spending under control or managing the dramatically inept war in Iraq. But for the most part, their heart just doesn’t seem to be in it any more. They’re like that tiny handful of people marching around in front of the clinic last week–but not on weekends and only if, y’know, the weather is nice.


Time was when you could really count on the fanatics. They had the holy light of God (or the holy light of murder–sometimes, they kinda look the same) in their eyes and a fire in their bellies. They would stop at nothing to save a child’s life–or at least, nothing short of, y’know, actually adopting an unwanted baby with cerebral palsey or something.

But today? Today we see one homeless man shaking his fist and pulling down trees. Kinda sad, really. Where’s the real spirit? Where’s the real chutzpah? Where’s the photo op of a bunch of True Believers standing in the rain? I wanted to take pictures, dammit!

Random weirdness

I get crap cell phone reception in my office, so I often have to go outside to take calls.

The day before yesterday, Shelly gave me a call at the office, and so i walked outside the office to talk to her. And found, lying on the ground, a bullet. A squashed and mangled bullet that had hit the side of the office building.

Big fucker, too…looks like a .44 or a .45.

The office building is under new management, and last week the new owners started putting up metal lath on the walls in preparation for a new coat of stucco. The bullet has the impression of the metal lath in it, so it was fired at the building somewhere in the past week.

What is it with this office building? It’s not in a bad part of town or anything, but first part of the building collapses, and now people are shooting at it! Fer Chrissakes…

Happy happy happy!

I should be on my way to see a client right now. Instead, I’m posting in LiveJournal, because I already know what the client’s problem is, and it’s user error, and we’ve been over this particular issue many times already, and the client can wait another five minutes ’cause I’m a bastard. 🙂

I am, however, a deliriously happy bastard.

For starters, smoocherie is going to be in town visiting us next weekend, and on top of that, I just got an email from an old friend I haven’t seen in about seven years saying that she’s in town as well and would like to get together some time this week. I’m really looking forward to spending more time with smoocherie, and the unexpected opportunity to see my friend is absolutely delightful.

And in two weeks, Necronomicon! It’s an annual science fiction convention, which means lots of cool people, drunken debauchery, strip “Are You a Werewolf?”, more freaks than you can shake a cat at (unless it’s a very patient cat indeed), and all the other con goodness that goes with science fiction conventions.

And feorlen is going to be in town in November. I haven’t seen her in forever, and I’m really looking forward to that, too… *bounce*

feorlen, you need to click this link. It’s…it’s…you just need to click it. Trust me.

On the financial front, there might actually be a light at the end of the tunnel for the electronics firm I’m associated with. For those of you not up on the ongoing saga there, I am a minority partner in a small, struggling electronics firm that makes storm detection gear, and has patents on the basic technology behind tornado detection equipment and bomb detection equipment. They’ve been searching for venture capital for quite a few years; the storm detection equipment is available and shipping, but the other gear is still in prototype form, and the company has been running on fumes for quite a while. This has had a disastrous effect on our financial situation, but as I type this, the principals of the company are working on a new source of venture capital that looks very promising indeed.

And if it doesn’t pan out, I may have a backup plan; a company that does high-end workflow and prepress software for the newspaper industry has expressed an interest in me, and is offering rather a good rate of pay.

And on top of all that, I’ve just been irrationally happy and exuberant the past several days.


I’m also sorting floppies.

I have a collection of about seven or eight hundred Mac floppies, some of whjich date back to the mid-1980s, containing software and archives of things I’ve worked on and old letters and images and everything else imaginable, but only have one computer left with a floppy drive that can read them. So I’ve been archiving stacks and stacks of floppies onto DVD. It’s been quite the trip down memory lane–letters I wrote to friends in 1989, scans of pictures of old friends, and an amazing collection of pre-PowerPC software and games and so on. (I have the original floppies of PageMaker 1.0, the first desktop publishing program; Photoshop 1.0, back when it was Mac-only and fit on a floppy; Microsoft Word’s first shipping release…we’re talking OLD stuff here!).

By the way, datan0de, I have a retardedly large stack of floppies of Amiga software, you interested?


And now off to see my client.

Because my server is back up, and it’s late, …

…and I have a sick sense of humor, and nothing better to do with Photoshop at 1:30 in the morning:

Those of you who are not addicted to World of Warcraft can move along, nothing to see here.

Okay, that’s weird…

So my business site is back up, kind of. You can’t surf to it–you get the Network Solutions “domain expired” redirect–but you can load images from it, and my FTP program shows all the files still there.

So I guess that images may or may not load in my journal over the next few days. Grr.

A perfectly sucktackular day…

In which our hero rants about things aggravating him, which are many, and then bends a meme to his own ends.

Okay, first of all, anyone who reads my journal right now won’t be able to see any pictures.

There’s a reason for this. The short form of the reason for this is that of the approximately six billion or so human beings on the planet, about five know how to behave with any maturity when things are emotionally stressful.

The long reason for this is that I have (or, technically, HAD) a business Web site, which once upon a time was registered with and hosted by a small local ISP called “Rapid Systems.” I used this ISP because it is owned by the brother of an old college friend and business partner of mine, and he and I had been friends for quite a number of years. He registered the domain in his own name, not mine.

Fast-forward to last year. My old college buddy and former partner has a falling-out with me, for two reasons: first, he decides (as is typical, it seems, for many people) that he’s going to take sides in my divorce, and second, he owes me money. Has owed me money for a long time. Apparently, he spent the money on something else and doesn’t intend ever to pay me back. So he decides to stop speaking to me, and (I’m assuming) his brother does likewise.

I contacted his brother several times to get the domain name transferred to my name; at first, he kept saying “okay, I’ll do that,” and didn’t, then eventually he stopped responding to me at all. So now the domain has expired. I can’t renew it because my name isn’t on the registration; I can’t re-register it because Network Solutions puts a hold on expired domains.

So you won’t be seeing any images in my LiveJournal until I get this all straightened out. Sorry. I used to host images on my personal site, but it’s been blacklisted by a lot of net blocking software, so until now I had been putting LJ images (save for anything, y’know, sexy) on my business site.

Oh, yeah, did I mention that it’s my business site that’s all screwed up?


So, the meme part. There’s this meme traveling around LiveJournal that tells you to put “[yourname] needs” into Google. Hilarity often ensues.

I did this, and was told by the Great Oracle Google that “Franklin needs a stadium,” “Franklin needs a few hot glue guns,” and “Franklin needs a good nickname.” Not really very interesting.

It gets more fun, though, if you try different variants. Want to see some real hilarity? Try Googling for “[yourname] eats” or “[yourname] hates” instead.

“Franklin eats by gathering five legs in one hand and then pulling the shell away from their still pulsating body.” “Franklin eats from blood stained baskets.” “Franklin eats all the doritoes, and Alby gets pissed, and decides he’s going to invent a bomb to kill frank.”

“Franklin hates the whole idea, but when a drunk gives him a silver dollar and gets him to play a slot machine, everything changes.” “Franklin hates everyone who can walk, and Winston hates everyone who is sober.” “Franklin hates it, but I have to admit, I’m fascinated by it. The amount of snot
that thing can suck down from one nostril is amazing.” “Franklin hates war, but it is his life.”

Hell, let’s keep going, this is fun!

Franklin punches Coach Yesutis and gave him a bloody nose because that was very funny.
Franklin opens the doors of the cabinet and pauses, looking round him suspiciously.
Franklin believes there has been a recent increase in the participation of a younger generation in same-sex activities.
Franklin screams again, praying for Death to come.
Franklin jumps from a helicopter and the bad guys fire machine guns at him.
Franklin tastes like dirt- I don’t recommend it.
Franklin has a diverse arsenal.
Franklin wishes to confine the ‘dark vast forest’ of the soul of man in a barbed-wire paddock.
Franklin knows what to expect from his foe, even with the improved war tactics.

I can’t log on to OK Cupid

Now, this might not ordinarily seem newsworthy, except that I can’t reach OK Cupid, either.

That, of itself, also isn’t newsworthy. What is newsworthy is the reason behind it, which has to do with corporate greed and very poor behavior on the part of some very big companies.

Two very big companies, to be exact. Level 3 Communications, an enormous and giddily spam-happy ISP, and Cogent Communications, an enormous and less spam-friendly ISP.

Cogent is pricing bandwidth very aggressively, and Level 3, they don’t much care for that. So Level 3 has ended its Tier 1 peering agreement with Cogent.

Essentially, in quick and hopefully not too technical terms, it means that two of the biggest carriers of Internet traffic are not speaking to each other right now. What that means is that the Internet has been split; for many end users, there is no way for people on one side of the divide to reach Web sites on the other, and vice versa. For example, right now most RoadRunner customers cannot reach OK Cupid.

Level 3 has been known to do this sort of shit before; in fact, there’s an article on Slashdot about it. Cogent is dealing with the problem by offering current Level 3 customers free connections to the Cogent network, on account of Level 3 being a bunch of mewling, lice-infested, pus-oozing filthy bastards and all.

Cogent Communications has released a statement about the issue. I can’t read it, because I’m on the wrong side of the divide and can’t reach Cogent’s servers.

By all accounts I’ve seen, Level 3 is being a bunch of right bastards here.

So if you’re having trouble reaching certain Web sites, that’s why.

Edit: Less than ten minutes after posting this, OK Cupid became reachable. Clearly, I should have complained sooner!

Preparing for the Future: Personhood Theory

We as a species have tended to have difficulty from time to time figuring out what makes someone a “person.” At various points in time, we’ve said that people with dark skin aren’t really “people,” or people who worship thus-and-such an imaginary friend rather than the imaginary friend we prefer aren’t “people;” hell, much of the world still believes, in this day and age, that women aren’t people, or that Jews aren’t people. The Tutsi tribe in Rwanda believes that the Hutu tribesmen aren’t people, and the opinion appears to be shared in the other direction.

And we ain’t seen nothing yet.

A lot of people don’t see it coming just yet, but it’s racing toward us with the ferocity of a freight train driven by a crack-addled monkey with a toothache: there’s going to come a time, and those of you on my friends list who are younger than I am will probably live to see it, when debates about whether or not black people have souls, and the attendant wars which have followed those debates, will look like a minor squabble at a Boy Scout camp.

So, as a public service for those of you who’re going to be faced with this particular poser, I offer a quick, easy rule you can remember when you’re trying to puzzle out the right thing to do:

If it’s sapient, it’s a person.

Gays? Yep, they’re people. Dark-skinned folk? Yep, they’re people, too. Stay with me, here.

Clones? People. Experimental monkeys with augmented brains? You got it–people. Artificial intelligences? Uh-huh…people. Constructs made by mapping a person’s brain into a neural network simulation? People.

Now, there are certain rules you have to live by when you’re dealing with people. First, if you do something, and after that thing you do, a person isn’t there any more, that probably isn’t cool. Switching off the AI? Dropping the clone into the waste-disposal chute? Murder. Even if the experiment didn’t go quite the way you intended.

Second, a funny thing about people is that you can’t own ’em and you can’t sell ’em; we’ve been through this already, and it’s a settled point, m’kay? Yep, even if you owned the computer you built the simulation on, as soon as the upload is done and the person you’ve uploaded looks through the Webcam you’ve thoughtfully hooked up and says “Whoa, so this is what it’s like to be inside a computer!” it ain’t your computer any more. Sorry. Maybe you can, I don’t know, take a tax writeoff or something.

If it’s sapient, it’s a person. Pretty simple really. That ought to help get you through a few moral conundrums.